Fundamentals of Immunology: Complement, MHC I and II, T Cells, and Cytokines
Course 2 is a four-course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material.
This is the second half of the journey through the defenses your body uses to keep you healthy. In the first part we learned about innate immunity and B cell function. The second part covers T cell function and coordination of the immune response.
Fundamentals of Immunology: Complement, MHC I and II, T Cells, and Cytokines builds on the first course to describe the functions of Complement, MHC presentation to T cells, T cell development and signaling. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. This course includes the structure of both MHC proteins and T cell receptors and the sources of variation. The course provides animations of gene rearrangement, developmental processes and signal cascades. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline.
What You’ll Learn:
How complement uses adaptive and innate triggers to target pathogens. The detailed structure and coding of MHC proteins and both alpha-beta and gamma delta receptors and how these proteins interact to initiate an adaptive immune response. The basics of signaling, and the varieties of external receipt and internal activation pathways. We bine the process of putting together how signals and crosstalk control the activity of the immune system.
Status: Infectious Diseases
Infectious Diseases
Status: Molecular, Cellular, and Microbiology
Molecular, Cellular, and Microbiology
Intermediate·Course·26 hours
Featured reviews
5.0
·Reviewed Jun 6, 2020
Incredible and amazing. There's no words to praise and thank enough for this astonishing course. The only zero I could see is the chance of you don't like it.
4.0
·Reviewed Jul 9, 2022
Not all the learning points are clear. It seems impossible to know the study points completely.
5.0
·Reviewed Jul 18, 2021
Absolutely wonderful course. So informative. I'm looking forward to the last two couses in the program.
5.0
·Reviewed Aug 26, 2020
It was very helpful course for me. I have learned different new thing about immunology from this course.
4.0
·Reviewed Jun 24, 2020
This course is good and it has built my interest in immunology.
5.0
·Reviewed Apr 6, 2020
Amazing course! Very complex material is explained in a logical and simple way using examples and analogues, which makes it easier to remember.
4.0
·Reviewed Feb 22, 2020
Although it could be dense, it is a very interesting course.
5.0
·Reviewed Jan 11, 2020
This course helps me get a basic understanding of immunology. It is beneficial for my further research.
5.0
·Reviewed Oct 24, 2020
Dr. Novotny did a great job in explaining complicated and daunting concepts in an easy to follow and fun way.
5.0
·Reviewed Apr 22, 2021
It s very useful. Actually I learnt many things regarding Tcell and signalling . Worth it....
5.0
·Reviewed Nov 8, 2023
Exact and insightful course that provides primary and advanced material for learners. Thank you
5.0
·Reviewed Jul 22, 2020
I have prior knowledge about this topic, still this course seems too hard for me.
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Showing: 20 of 76
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R
Rodrigo
5.0
·Reviewed Jun 7, 2020
Incredible and amazing. There's no words to praise and thank enough for this astonishing course. The only zero I could see is the chance of you don't like it.
M
Momchil
5.0
·Reviewed Mar 5, 2020
Amazing lecturer! I will be keep on coming back to the material! very challenging exams and a lot to learn! Absolutely turned on my curiosity mood! Deeply thankful for the course!
D
Durbar
5.0
·Reviewed Dec 14, 2019
lectures are good. may have to go through the course guide provided before final exam
V
Vinod
5.0
·Reviewed Mar 30, 2020
Excellent module which covers in depth knowledge even at molecular level
M
Malvina
4.0
·Reviewed Jan 10, 2020
A good course, but the impression is spoiled by minor flaws. The quality of this course is slightly worse than that of the first part.
D
David
5.0
·Reviewed Feb 15, 2019
This was a very amazing course. The teacher is very good! She explains everything in a very interesting way. Immunology can be confusing but she somewhat make it easy to remember. I liked the "artsy" proteins and things she used to explain. I also liked the organization of the course. I would suggest improving a little bit the video and sound, and adding some animations, for example for signaling or conformation changes. I would recommend you to take this course if you want to understand more about T cells and overall immunology terminology. The "level" wasn't that hard but it was not easy. You need some kind of biology/biochemistry knowledge to acquire most of the info.
M
Mary
5.0
·Reviewed Aug 18, 2020
This is a challenging subject, chiefly because most things are named by letters and numbers - IL-4, CD-8, c5, JAK-STAT, etc. Sometimes, the immunologists go wild and use Greek letters, which actually makes things more difficult to remember, because alpha, beta, gamma and delta are used in many disparate places. It makes terms like "calmodulin", which sounds like a SoCal transportation system, a welcome change. This is a well-taught course about a difficult subject. I give me a bit of the existential heebie-jeebies to know all this is going on in my body without my slightest notice.
H
Hilary
5.0
·Reviewed Jun 9, 2020
This is a very high quality-taught course at a very attractive price. The professor explained everything in a clear and concise manner. Her use of visual aids and analogies made memorizing new concepts much easier for me. I am looking forward to the next course in this immunology specialization. I highly recommend this course.
S
Sveta
5.0
·Reviewed Sep 27, 2020
Dear Alma moon Novotny, thank you very much for your work!!! You have given me a lot of knowledge, which I will share with my students in Russia. I also teach immunology, but I've never heard anyone better than you. This is the highest bar!
....and Now I love owls too)))
M
Mohamad
5.0
·Reviewed Mar 20, 2020
One of the best courses I ever learned on Coursera
The professor is cheerful and professional in teaching methods; she was using very interesting ways to tell the information. I hope one day I can meet her and work in her research group.
F
Fabienne
5.0
·Reviewed Mar 28, 2020
Module 2 out of 3. It was a great experience, once again, done by an excellent teacher! Thank you for offering this specialization course, can't wait to start module 3!
Y
Yuviana
5.0
·Reviewed Jul 11, 2020
It is the best course to brush up your knowledge in Immunology. Precise and relevant. Every aspect has been touched and clearly explained with very good analogies.
I
Irina
5.0
·Reviewed Apr 7, 2020
Amazing course! Very complex material is explained in a logical and simple way using examples and analogues, which makes it easier to remember.
U
Urmila
5.0
·Reviewed Aug 27, 2020
It was very helpful course for me. I have learned different new thing about immunology from this course.
R
Rui
5.0
·Reviewed Jan 12, 2020
This course helps me get a basic understanding of immunology. It is beneficial for my further research.
A
Asif
5.0
·Reviewed Jul 23, 2020
I have prior knowledge about this topic, still this course seems too hard for me.
P
prashanna
5.0
·Reviewed May 4, 2020
Excellent content and excellent supervising from the instructor. Thank you.